Aceon is an ACE inhibitor. It is essentially a pro-drug, which promotes the formation of the active metabolite of perindopril in the body.
It all leads to a decrease of post-load and preload, and resistance of the pulmonary vessels, increase of the minute volume of the heart and increase of tolerance to the load.
The drug reaches a maximum effect within 4-8 hours after reception, the effect acts about a day. The drug is excreted from the body by the kidneys.
Initially this drug is taken 1-2 mg at a time once a day. You can then move on to supporting dose, which is two times more if the patient manifests congestive heart failure, or 4 times more, if they have hypertension. In any case, you should take the drug at one time.
The drug is quite effective in a number of different problems related to heart and blood vessels, but is primarily used for the following problems:
- heart failure chronic;
- arterial hypertension;
- prevention of recurrent stroke – after, respectively, a stroke, or violations of cerebral circulation of transistor category of the ischemic type – but only as part of combined therapy.
In some situations, the use of this drug is contraindicated and should not be recommended – it can theoretically lead to unwanted negative consequences.
These situations include
- hypersensitivity to a key component of the drug, or side components;
- pregnancy and breast-feeding;
- General hypersensitivity to ACE inhibitors.
There are situations when, theoretically, the use of this drug is permissible but very undesirable. In this case, you should consult your doctor to find out what you should do in your situation in order to effectively minimize risks.
Such situations, among others, include
- edema of angioneurotic type in the history of the therapy, carried out by using ACE inhibitors, and idiopathic or hereditary edema of angioneurotic type;
- renal artery stenosis of bilateral type, as well as stenosis of the artery of a solitary kidney;
- period after kidney transplantation;
- renal failure chronic (especially one that is accompanied by hyperkalemia);
- a diet which is noticeably restricted to Na+;
- aortic stenosis;
- Cerebro- and cardiovascular diseases, including coronary insufficiency, ischemic heart disease, cerebrovascular insufficiency and so on;
- severe systemic connective tissue diseases of autoimmune type – they include, among other things, red systemic lupus, scleroderma and so on;
- diabetes – may increase the effect of hypoglycemic drugs;
- old age;
- young age – approximately before eighteen years of age;
- a condition where total blood volume decreases.
This is only part of these states, so it is advisable to ask the doctor whether the treatment with this drug is valid for you at the moment.