Drug Description

Adipex-P is a medicine that reduces appetite and helps to lose weight. Its generic is called Phentermine. Adipex-P is usually used as a weight loss drug. However, it can be also prescribed to the people with hypertension, increased level of cholesterol, diabetes and other health problems where obesity can enhance the risk of their illness.

Essential information

Adipex-P is contraindicated to the pregnant and breastfeeding women (as well as any other weight loss medications).
Patients with cardiovascular diseases, kidney or renal dysfunction, brain and pancreas disorders, thyroid problems, mental disorder or any other serious health problems must not use this drug before consulting the doctor.
Avoid taking this drug without the prescription, if you suffer from any serious disease. Inform the doctor about all the drugs you’re currently taking.
Children under the age of 16 must not take the drug. Avoid taking the medicine longer than necessary. Don’t drink alcohol during the treatment.


The average dosage for adults is 18.75-37.5 mg a day. However, this is the common dosage advice, which is not suitable for everyone. Always stick to the doctor’s recommendations. Take the drug at least 6 hours before sleep.
The most common dosage is 37.5 mg. This drug can be taken only by people older than 18. The effect of Adipex-P increases in combination with a regular exercise and a balanced diet. A single dosage can be taken one hour before or two hours after the meal.

Skipping the dose/overdose

Exceeding the dose of Adipex or taking the drug less than 8 hours after the previous dosage may cause overdose which can may be fatal. In case of overdose, seek immediate medical assistance.
If you missed the dosage, you should take it as soon as you remember. However, if it’s already time for the next dose, you should skip the missed one.
Avoid taking two dosages at once.

Adverse effects

The use of Adipex-P may cause adverse effects. They are divided into two types: less severe and severe adverse effects.

Less severe adverse effects

  • Dryness in the mouth
  • Sickness
  • Vomiting
  • Vertigo
  • Sleeping disorders
  • Constipation
  • Stomach upset
  • Fatigue

Severe adverse effects

  • Serious mental problems
  • Decrease in physical capacity
  • Increased heart rate
  • Tremor
  • Breast pain

Don’t worry about the minor adverse effects. However, if you note the severe side effects, you should seek immediate medical assistance.


Adipex-P interacts with most weight loss medications, such as fenfluramine, dexfenfluramine and may lead to severe lung diseases, such as pulmonary hypertension. Therefore, take Adipex-P with great caution.
Avoid taking Adipex-P if you’re already taking other weight loss medications like Meridia or Xenical.