The active ingredient of Amoxil is amoxycillin trihydrate. This ingredient is a synthetic analogue of amino-penicillin. It has a bactericidal effect, but is not sensitive to microorganisms, capable of producing penicillinase. Amoxil contains a very important for therapeutic purposes clavulanic acid, which makes the drug resistant to penicillinase, reduces the degree of cross-resistance to antimicrobial drugs.
Antibiotic refers to a group of amino-penicillins, has a broad spectrum action. Inhibiting the synthesis of cell wall, the drug exerts a bactericidal effect. It is active against staphylococci, streptococci, Corynebacterium diphtheria, Enterococci, Escherichia coli and Haemophilus sticks, Neisseria gonorrhea and meningitis, Proteus, Salmonella and Shigella; and anaerobes – Clostridium, Peptostreptococci and peptococci.
In case of simultaneous use with metronidazole, the drug is effective against Helicobacter pylori.
Indications for use
Amoxil can be assigned in the following cases:
- For the treatment of infectious diseases of the gastrointestinal tract and hepatobiliary system
- For the treatment of infectious diseases of the kidneys and urinary system of the body
- For the treatment of infectious diseases of joints and bone tissue
- For the treatment of infectious diseases of the skin and soft tissues
Amoxil is also effective in case of infectious complications in the postoperative period.
The treatment of ulcer of digestive tract and chronic gastritis is based on the combination of Amoxil with metronidazole or clarithromycin.
Method of application and doses
The range of doses using Amoxil is very wide. The dose, frequency of administration and duration of treatment are set individually by the doctor.
In case of an infection of easy and moderate severity the drug is taken for 5-7 days. However, in case of infections caused by Streptococcus, the duration of treatment should be not less than 10 days.
In case of the treatment of chronic disease, the local infectious lesions, infection with severe course, the doses should be determined taking into account the clinical picture of the disease.
The drug should be continued for 48 hours after disappearance of symptoms.
Amoxil may be used to patients with renal insufficiency.
In case of violation of the liver, the dose adjustment is not required.
Amoxil can be taken regardless of meals. The tablet should be swallowed with liquid.
During treatment the patient is advised to drink more fluids than usual.
Children. Children up to 5 years are prescribed the other dosage forms of amoxicillin.
Hypersensitivity to amoxicillin trihydrate, other components of the drug and/or other P-lactam antibiotics; infectious mononucleosis, lymphatic leukemia; breast-feeding.