Drug Description

Benadryl (the brand name of Diphenhydramine), is a cough medicine sold in oral and topical form (it means that this medicine must be applied only on a certain area).The drug was approved by FDA (1946).
This drug is usually considered a non-prescription medicine. It is also known under different brand names in different countries as a drug for the treatment of motion sickness and to have a good night rest.


Benadryl is usually used for the treatment of head cold, sneezing, nasal and throat itching and other allergic reactions. The active component of this drug (Diphenhydramine) blocks the chemical histamine that happens naturally in the body. This drug is available in cream, ointment and spray and may be used to relieve itching caused by insect bites and irritation caused by sun burn.


Benadryl capsules is available in the following dosages: 50 mg and 25 mg. 25 mg capsules contain 25 mg of active substance. It must be swallowed whole (when take in the form of pill). When it is taken in the form of syrup for children, parents should give them 1 to 2 teaspoons of the syrup. As for the pill, take 1 or 2 pills a day.
Benadryl syrup must be taken only with the measuring cup that comes with the drug. The medicine is available only on the doctor’s prescription.
Benadryl must be taken by pregnant women (but only on the doctor’s prescription), as it can’t harm the baby. However, breastfeeding women shouldn’t take this drug, as it can affect the newborn babies.

Adverse effects

Common adverse effects caused by the use of this drug are: too long duration of sleep, head pain, dryness in the mouth, etc. In case of severe adverse effects as breathing difficulty or blurred vision, you should stop the treatment and seek immediate medical assistance.

Contraindications to Benadryl

The drugs that interact with the medication are Doxepin, Aspirin, Diazepam, Lorazepam and other drugs containing the active substance called Diphenhydramine. Therefore, you must consult a doctor before using any of the above-mentioned medicines together with this drug.
Patients with such diseases as hypertension, hyperthyroidism, increased eye pressure, bowel disorders, peptic ulcer, enlarged prostate gland, closed angle glaucoma and urinary retention.
Avoid drinking alcohol during the treatment, as it may change the drug effect.