Capoten is a drug intended for the reduction of arterial pressure, caused by hypertension of different genesis. The active substance of this drug is captopril that blocks the mechanisms of vascular spasm and prevents the dissolution of vasodilating components. The use of Capoten aggravates the general peripheral vascular, arterial and venous resistance and pressure on the heart. At that, the cardiac output doesn’t reduce, and may even increase as the kidney blood flow. It doesn’t cause the retention of liquid, as some other vasodilators. Capoten is used successfully in combination with the other drugs, such as diuretics or the drugs improving vascular blood flow and brain nutrition– Glycine, Actovegin, etc. It all allows using this medicine for the treatment of hypertension, chronic congestive heart failure, recent myocardial infarction, diabetic and autoimmune neuropathy, congenital cardiomyopathy, etc.
Capoten is available in pills. You can find an individual dosage of this drug and information about this use in the instruction. This drug can’t be used in the following cases: expressed kidney diseases, including after the kidney transplantation; progressive stenosis (narrowing) of renal arteries; high level of blood potassium, primary hyperaldosteronism, inherited Quincke’s disease; individual intolerance of the drug components and its analogs– Prestarium and others. The treatment with Capoten is contraindicated to the pregnant and lactating women because of the confirmed risk of fetal anomaly and death, as well as pathologic effect on the baby. Children also shouldn’t use this drug. In extreme cases, children can receive microscopic doses under the constant medical supervision.
Side effects and overdose
Capoten has a very wide range of side effects (which are rare, according to the instruction). The main risk group is patients with autoimmune diseases, violations of blood composition and kidney dysfunction. You can note the adverse effects in the nervous system and sensory organs, dysfunctions of cardiovascular, urinary, breathing, digestive systems and skin, as well as different kinds of allergic reactions. Some patients (especially women) suffer from the dry cough, increased body temperature, pains, acidosis, etc. The overdose can have lethal outcome and requires immediate reanimation.