Ceclor

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Description

Ceclor is cephalosporin antibiotic of the 2nd generation for per-oral reception. The drug has bactericidal effect.

It has a wide range of antimicrobial actions. The drug is highly active against gram-negative microorganisms (Escherichia coli and Haemophilus influenzae, Salmonella, Shigella, enterobacteria, Proteus mirabilis, Klebsiella, gonorrhea). It is also active against gram-positive microorganisms(Staphylococcus, Streptococcus).

Ceclor is resistant to beta-lactamase. Anaerobic microorganisms: bacteroides, peptococci, peptostreptococci are sensitive to the drug. IT is inactive against various species of Pseudomonas daddy, most strains of enterococci, many strains of Enterobacter cloacae, methicillin-resistant Staphylococcus aureus and Listeria monocytogenes.

Ceclor indications

  • Autocrine and purulent media otitis
  • Acute unspecified pharyngitis
  • Acute upper respiratory infection of multiple and unspecified localization
  • Pneumonia without specifying the causative agent
  • Chronic sinusitis
  • The syndrome of staphylococcal skin lesions in the form of algophobic bubbles
  • Infectious myositis
  • Abscess of tendon sheath
  • Other infectious synovitis
  • Abscess of the shoulder Bursa
  • Other infectious bursitis
  • Gonococcal infection
  • Acute unspecified tonsillitis
  • Cystitis
  • Urethritis and urethral syndrome
  • Urinary tract infection without established localization
  • Gonococcal inflammatory diseases of female pelvic organs

A course of treatment and dosage

For adults the drug is prescribed with average single dose of 250 mg, the multiplicity of reception – 3 times per day. The maximum of daily dose of the drug Ceclor is 4 g per day. A daily dose for children is 20 mg/kg of body weight, the multiplicity – 3 times a day. The maximum daily dose is 40 mg/kg. Children should take a drug in suspension. Injections are intramuscular or intravenous: adults: 750 mg 3 times a day, in case of severe infections 1.5 g 3 times a day. The duration of treatment is 7-10 days.

Drug Contraindications

Hypersensitivity to cefaclor and other cephalosporins.

Side effects are nausea, vomiting, diarrhea, allergic skin reactions, change of the composition of the blood, soreness at the injection site.

Overdose of Ceclor

The symptoms of overdose are nausea, vomiting, diarrhea. The treatment is protection of the respiratory tract of the patient, providing the necessary ventilation and perfusion, control and maintain of blood gases and serum electrolytes at the required level.

The degree of absorption of the drug from the gastrointestinal tract can be reduced by reception of activated charcoal. There wasn’t shown the clinical efficacy of forced diuresis, peritoneal dialysis, hemodialysis and hemosorption with an overdose of cefaclor.

Interaction with other medications

Aminoglycosides enhance the effects of cefaclor, chloramphenicol, tetracycline, erythromycin, sulfonamides reduces.

There is a small number of reports of increased anticoagulant effect of anticoagulants in cases of their simultaneous reception with cefaclor. The absorption of Ceclor from the gastrointestinal tract is reduced, if within an hour after reception you will take antacids containing magnesium or aluminum hydroxide. Probenecid slows excretion of the drug by the kidneys.