Colospa is a drug that was created to reduce the acidity of gastric juice. Active substance of the drug is esomeprazole that decreases both basal, that is, permanent and induced, i.e. caused by stimuli, production of hydrochloric acid. There is long description of the benefits of Colospa in front of all the drugs precursors, for example, Omez, it leaves no doubt in choosing to treat conditions like reflux esophagitis, ulcers of the stomach or duodenum caused by the bacterium Helicobacter Pylori or nonsteroidal anti-inflammatory drugs such as Aspirin, Diclofenac and so on, idiopathic hypersecretion. This medicine greatly reduces the period of therapy, makes treatment more efficient, can be used for further supportive therapy – prevention of the already cured illnesses.
Colospa is released in the form of tablets and intravenous solution. The instruction of the drug notes that it should be taken without chewing or crushing. In extreme cases, it is allowed dissolution of the tablet in half a glass of still water. Even with this method it is impossible to chew sludge from microgranules. If a patient isn’t able to swallow, Colospa is administered as a suspension through a nasogastric tube. The various medical conditions require special regimens of the drug. In case of disorders of the kidneys or liver of average severity, the correction of doses of the drug isn’t required. Colospa is not prescribed in case of severe renal disease, individual intolerance of the drug and, fructose, in conjunction with the inhibitors of the proton pump, to children under the age of twelve. Children older than twelve years old can use this medicine in case of the diagnosis of “gastroesophageal reflux”. There are no adequate clinical data on the use of the drug during pregnancy, but in laboratory tests it has not revealed any effect of the drug on the fetus. Due to the fact that the components of the drug are excreted in breast milk – it is not prescribed to lactating women.
Side effects and overdose
The action of this drug is systemic, therefore, in addition to the digestive system, it can affect other organs. So, in addition to various dyspeptic symptoms, Colospa can cause dizziness, headaches, sleep disturbances, emotional distress, violations of the blood, swelling, pain in joints and muscles, general malaise and so on. Allergy to components of the drug can be expressed as in the occurrence of urticaria, and in severe forms of shock, angioedema, bronchospasm.
In case of significant overdose, there is possible deterioration in general health and digestive disorders. Treatment is symptomatic.