Drug Description

Cymbalta, also called Duloxetine, is a tranquilizer. It is usually used for the treatment of depression by impacting certain brain chemicals (norepinephrine and serotonin) that are unbalanced because of anxiety.
Moreover, Cymbalta can be used for the treatment of disorder associated with fibromyalgia. Sometimes it is also used for the treatment of back and joint ache or chronic muscle pain also called osteoarthritis.
For kids (especially those older than 7 years), Cymbalta is the best option for the treatment of anxiety.

Important information

Don’t take Cymbalta if you have glaucoma.
If you’re taking thioridazines, then you should avoid taking this drug. The use of Cymbalta is not allowed if you’ve taken any MAO inhibitors in the past 2 weeks, as it may cause some undesirable adverse effects. Certain inhibitors include the injections of methylene blue, phenelzine, tranylcypromine and linezolid.
If your treatment course has ended, you should wait at least for 7 days before taking MAO inhibitor to prevent any undesirable adverse effects.
Suicidal thoughts are widespread in the teenagers, particularly within the first week of treatment.
If you note some mood swings or behavioral changes, increased anxiety, sleeplessness or bouts of anger, inform your doctor immediately.
During the treatment with Cymbalta, contact your doctor at once if your depression gets worse or you have suicidal tendencies.
Patients with allergy to the main active component Duloxetine must avoid using Cymbalta.
Inform your physician about all your diseases, especially the following: epilepsy, cramps, liver or kidney failure, bipolar disorder, glaucoma, hemophilia, sickle cell anemia, increased blood pressure or drug addiction, etc.
If you take Cymbalta during the III trimester of pregnancy, side effects are possible, as the impact of this drug on fetus is unknown.
Therefore, it is essential to inform your doctor if you’re pregnant or planning a pregnancy during the treatment with Cymbalta.
Lactating women shouldn’t take this drug, as it can be harmful to the child.
Minors can’t use this medicine without the doctor’s recommendation.


Cymbalta is sold in the following dosages: 20mg, 30mg, 40mg, 60mg and 120mg. The dosage is prescribed according to the patient’s age, health condition and reaction to the drug. Take this drug orally once or twice a day irrespective of the mealtime. Patients with sickness can take this with the meal. Swallow the capsule and don’t mix the drug contents with meal or water as it may cause adverse effects. Take the drug every day at the same time to achieve the desired effect.

Skipping a dose/overdose

You should take the drug at the same time each day; it will help you prevent skipping the dose. If you have skipped a dose, you should take it as soon as possible. If it’s time to take the next dose, you may take only one dose. In case of overdose, immediately seek the medical assistance.

Adverse effects

Patients have different responses to Cymbalta; some people can experience adverse effects. The most widespread adverse effects are:

  • Perspiration
  • Vision impairment
  • Lack of appetite
  • Dry mouth
  • Fatigue, vertigo or sleepiness

If these symptoms last too long, talk to your doctor immediately. Other possible adverse effects are: change in behavior or mood swings, sleeping issues, panic disorders, anxiety, restlessness, depression, aggressiveness, impulsiveness and hyperactivity.


Don’t consume alcohol during the treatment as it may cause side effects. Some anti-inflammatory drugs such as Ibuprofen, Aspirin, and naproxen may also lead to contraindications.