Furosemide is the so-called a loop diuretic, i.e., the strongest diuretic. It promotes the excretion of trace elements: chlorine, sodium, magnesium, calcium and potassium. This drug has an effect on the filtering system of the kidneys. This activity leads to the use of Furosemide during the fluid retention of various origins: problems with human heart, liver or kidney, hypertensive crises, edema of the brain and so on.

Indications for use

  • Swelling of heart or renal origin;
  • high blood pressure that accompanies chronic renal failure.

This medicine is taken orally. The dose is determined by severity of illness, and the period of its flow.

Drug contraindications

Furosemide shouldn’t be used in case of severe stages of renal, hepatic or cardiac disorders – with hepatic coma, acute myocardial infarction, urinary retention more than a day and so on. Some violations of water-salt metabolism also are contraindications to receiving Furosemide. There are patients with individual intolerance to components of the drug and other drugs of sulfonamides group. There are limits to treatment with Furosemide for pregnant and lactating women. During pregnancy the drug should be taken under the control of a doctor. The medicine can be transferred with breast milk and suppress lactation, therefore its use is not compatible with continued breastfeeding.

Furosemide is strictly forbidden to treat people with the following symptoms and diseases:

  • Individual intolerance of the drug components.
  • Stenosis of the urethra.
  • Acute renal failure, which is accompanied by anuria.
  • Hepatic failure severe.
  • Hyperglycemic  coma.
  • Hepatic coma.
  • Hypochloremia.
  • Acute glomerulonephritis.
  • Hypertension.
  • Hypokalemia.
  • Obstruction of the urinary tract.
  • Hyperuricemia.
  • Lupus erythematosus.
  • Myocardial infarction.
  • Digitalizing intoxication.
  • The various manifestations of violations of water-salt exchange.
  • Very high central venous pressure.

It is not recommended to use tablets in case of:

  • Diabetes.
  • benign prostatic hyperplasia.
  • Hypotension.
  • Atherosclerosis of cerebral arteries.
  • Hypoproteinemia.
  • Hepatorenal syndrome.

Side effects

  • Disorders of the cardiovascular system (arrhythmia, collapse, hypotension, and other diseases).
  • Headache, accompanied by dizziness.
  • Convulsions.
  • The weakness with lethargy and other irregularities in the functioning of the central nervous system.
  • Violations of the perception of auditory and visual organs.
  • Disorders of the digestive system (constipation, anorexia, pancreatitis, nausea with vomiting, etc.).
  • Acute retention of urine.
  • Impotence.
  • Hematuria or oliguria.
  • The manifestations of allergic reactions (skin itching, urticaria, fever, purpura, anaphylactic shock, etc.).
  • Thrombocytopenia.
  • Leukopenia.
  • Hypomagnesemia.
  • Hyperglycemia and other various diseases associated with metabolic disorders and electrolyte balance.