Indications for Ilosone use: treatment of infectious process of easy and average degree, caused by bacteria, for all infants of following groups; prevention of gonococcal ophthalmia; as prokinetics to enhance motility in gastrointestinal pathology.
Ilosone is ingested between meals 2-4 times a day.
Children: Ilosone is taken 30-50 mg per 1 kg of body weight per day. The dose is divided into 4 admissions. The daily dose of the drug for children from 1 to 3 years is 400 mg for children from 3 to 6 years – 500-700 mg, for children 6 to 8 years — 750 mg, for children from 8 to 12 years — 1000 mg.
For the treatment of child pneumonia, Ilosone is indicated for 50 mg per 1 kg of body weight per day.
12 years old children and adults take 250 mg-500 mg of the drug 4 times a day. Single dose should not exceed 500 mg, the daily dose is 2000 mg.
The course of treatment and frequency of Ilosone intake is decided in each individual by case your physician.
During pregnancy: the drug is prescribed according to strict medical indications, when risk from a disease of the mother is higher than the risk of the impact of the drug on the fetus.
In case of the use of medication during breastfeeding of the newborn, the child is transferred to artificial adapted dairy mixes. In 2-3 days after finishing the course of treatment, breastfeeding can be resumed.
Ilosone is appointed for children who are 1 year old and older.
Hypersensitivity, significant hearing loss, concomitant use of terfenadine or astemizole, pregnancy (erythromycin estolate).C caution. arrhythmia (history), prolongation of Q-T interval, jaundice (in history), hepatic and/or renal failure, lactation.
Side effects of Ilosone
Dyspeptic disorders, disorders of the liver, cholestatic hepatitis, jaundice, lesions of the ear, arrhythmia, super-infection, allergic reactions, stomatitis, epigastric pain, candidiasis mouth and the perianal area.
Transient cholestatic hepatitis and allergic reactions are rare.
The drug can cause an increase in plasma concentrations of theophylline, digoxin, and carbamazepine.
Ilosone may cause vomiting at feeding to children with hypertrophic pyloric stenosis (GSP) (there are reports that 5% of cases in the prevention of pertussis erythromycin has developed such complications). In case of the introduction of high antimicrobial doses (30-50 mg/kg/day.) for > 14 days the newborns under 2 weeks had a tenfold increased risk of developing hypertrophic pyloric stenosis. The cardiotoxic effect is amplified during taking of erythromycin, the risk of arrhythmia is reduced by slow infusion of the drug (within 1 hour).