Drug Description

Imuran belongs to the immunosuppressants, usually used after kidney transplantation. This is a prescription drug that was considered one of the most popular immunosuppressants for over half a century.
The main active component of this drug is azathioprine, which acts by minimizing the effect of certain immune system cells in the human organism.
Imuran also belongs to the group of antimetabolites (i.e. the substance that combines with the enzymes inside the cells to interfere with their normal metabolism). Therefore, the medicine can easily control the human immune system.


Imuran is intended to help the body adjust to the new kidney and impede its rejection after the transplantion. Therefore, it is commonly used in combination with other immunosuppressant drugs.
Moreover, Imuran is intended for relieving the symptoms of rheumatoid arthritis (for example, inflammation). For that purpose, it can be used in combination with the other drugs. Due to the function of the drug, any misuse can cause great damage.


Different patients require different dosages of Imuran to prevent the rejection of transplanted organ. Some patients who are sensitive to the drug may be suggested an alternative treatment. The initial dose for the treatment of rheumatoid arthritisis 50 to 100 mg.
Usually, patients should take a single dose of Imuran a day. However, if the patient thinks that the drug’s effects are too powerful, the dose can be divided into several intakes.
Imuran must be taken orally (by mouth) irrespective of the mealtime. The maximum daily is 250 mg.

Adverse effects

The common adverse effects of Imuran are:

  • Vomiting
  • Contagion
  • Leukopenia

Severe adverse effects of Imuran are:

  • Breathing difficulty
  • Liver dysfunction
  • Pain in the joints and muscles
  • Blistering
  • Regular bleedings

Drug interactions

Imuran may interact with different drugs: blood thinners, aminosalicylates and alkylating agents. Inform your doctor if you’re using any of these drugs or other prescription medicines.