Lasix is a diuretic drug. The active ingredient is furosemide. This component is included in other medications. Treatment with this diuretic has a rapid and powerful effect – it comes after an hour and lasts for about six hours. It increases the amount of urine; salts of sodium, calcium, magnesium, potassium are excreted from the body. Chloride ions are excreted in connection with the sodium (salt NaCl).
Reducing the volume of circulating blood and directly acting on the system of regulation of tone of the vascular walls, Lasix affects blood pressure and heart function.
So, veins swell, reducing preload on the heart, pressure in the left ventricle also decreases. However, if the health of the kidneys is markedly disturbed – the effect will be weak.
Lasix is used in cases when
- Edema caused by chronic kidney or heart failure
- Edema and kidney failure during pregnancy or burns
- Edema caused by nephrotic syndrome
- Edema caused by liver diseases
Lasix is released in the form of tablets and solution, which is taken intravenously or intramuscularly. The tablets should be taken before meals with a a lot amount of water. The instruction of the drug emphasizes that the treatment always starts with the lowest dose that is gradually increased until sufficient one to determine the normalization of the status of the patient. The daily dose should be divided into several ones to make the drug enter the body evenly.
Usually you should begin treatment with 20-80 mg of Lasix a day. If long-term use is necessary, the daily maintenance dose is usually 40 mg.
Lasix is contraindicated in cases of
- The lack of urine and the lack of response to the drug (patients with renal failure)
- Reduced concentration of potassium or sodium in the blood
- Reduced blood volume
- Hepatic coma or precoma
- Violated outflow of urine caused by any reasons
- Poisoning by digitalis
- Acute glomerulonephritis
- Elevated levels of uric acid in the blood
- Elevated central venous pressure (more than ten mm Hg. calendar)
- Some lesions of the heart, for example, decompensated mitral or aortic stenosis
- The treatment of children during the first three years of life
- Pregnancy and lactation
- Intolerance to certain drugs such as sulfa antibiotics
- Low pressure
- Myocardial infarction
- And many other diseases and conditions
Side effects and overdose
Lasix has a multilateral and strong effect on all systems of the body. The excretion of excessive volume of fluid, trace elements and salts can lead to seizures, disorders of the nervous system, heart and so on.
It can also cause too strong lowering of blood pressure, fraught with weakness, confusion and other symptoms. Other possible side effects:
- Acute urinary retention
- Disorders of glucose metabolism
- Nausea, constipation or diarrhea
- Hearing loss (reversible)
- Disorders of the blood
- Allergic reaction