Lizinopril

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Description

Lizinopril belongs to the ACE inhibitors. Once in the body, Lizinopril normalizes blood pressure, PR, and the pressure in the capillaries of the lungs. Individuals with heart failure help to improve the tolerance of cardiac muscle to stress, to improve blood flow to the affected myocardial ischemia, to reduce the hypertrophy of the cardiac muscle and arterial walls.  The prolonged use of Lizinopril increases life expectancy in people with heart failure. In the case of hypertension the beneficial effects of the drug is observed on the first days of treatment, and the pressure stabilizes in 30-40 days.

Indications for use

Lizinopril is recommended for use in the following cases:

  • arterial hypertension (monotherapy or in combination with other antihypertensive drugs);
  • heart failure (together with other funds);
  • struggle with acute heart attacks at an early stage (in the first 24 hours to prevent left ventricular dysfunction);
  • diabetic nephropathy (treatment for persons with type 1 and type 2).

Analogues of Lizinopril

The analogues of Lizinopril on the active substance are medicines such as April, Liziamma, Sinopril, Lizonorm, Litan and Prinivil.

How to take Lizinopril

You should take the drug at the dosage of1 p/day, preferably at the same time. In case of hypertension you should start treatment at the dosage of 10 mg, gradually moving to 20 mg of Lizinopril per day. The maximum dosage should not be higher than 40 mg of the drug.

In the case of chronic heart failure you should start receiving Lizinopril at the dosage of 2.5 mg, drinking a pill a day. Every 5 days the dose should be increased to 2.5 mg, bringing it to the dosage that was prescribed by a doctor (maximum 20 mg).

In case of myocardial infarction you should take 5 mg of Lizinopril the first two days, then you may increase the dosage to 10 mg/day. Individuals with acute heart attack should take this remedy for at least six weeks.

In order to fight with diabetic nephropathy this medication should be taken at the dosage of 1 p/day, 10 mg. If necessary, a doctor may decide to increase dosage up to 20 mg/day.

Drug contraindications

There are a number of states when you are not recommended to take Lizinopril

The instruction includes the following diseases:

  • cerebrovascular pathology;
  • aortic stenosis;
  • inhibition of bone-marrow bleeding;
  • kidney failure;
  • hyperglycemia;
  • primary aldosteronism;
  • angioedema;
  • hypersensitivity to Lizinopril;
  • lactase deficiency or lactose intolerance;
  • the state of pregnancy, breast-feeding;
  • the age of 18.

Side effects

Lizinopril can cause such uncomfortable symptoms as: tachycardia, bradycardia, decrease in blood pressure, anuria and uremia, renal failure, anemia, and bronchospasm. However, these conditions are extremely rare. Patients often note the appearance of shortness of breath, dry mouth and some dyspeptic symptoms. The allergic reactions aren’t ruled out as well.