Nitroglycerin is a drug belonging to the group of nitrates, which action is directed against heart and vascular pain, and seizures. The mechanism of the effect of this drug is associated with the relaxation of smooth muscles of the vascular wall – thus, the vessels, mainly the veins, expand. Less blood volume enters the heart, reduces vascular resistance in the outflow from the heart – thus, the load on this important organ is removed. The heart muscle itself, in this context, feels less need for oxygen supply. There is the redistribution of blood flow – it is provided to areas lacking blood supply. All this leads to frequent use of Nitroglycerin for angina, myocardial infarction, and, pulmonary edema, during surgical operations and so on.
This drug is available in different pharmacological forms: in the form of sub-lingual pills, drops, aerosols; films and patches of adhesive on the gums and skin; long-acting tablets and capsules; solution for injections. The medical and emergency reception and selection of doses are described in the instruction of the drug. During an acute attack of angina a tablet or two of Nitroglycerin should be placed under the tongue and resolved. For the fastest effect, it is permissible to crush it with your teeth. It is possible to repeat it not earlier than in half an hour. In case of weakening of pain, if there is a part of pill left in the mouth, you can spit it out. Drops are dripped directly under the tongue, one to two, or a lump of sugar, two or three, and are resolved.
You shouldn’t use Nitroglycerin if: you are hypersensitive to nitrates; have shock circulatory disorders, collapse, very low blood pressure, and myocardial infarction; acute stroke, traumatic brain injuries, if you take it together with Viagra; in case of severe anemia; toxic pulmonary oedema; angle-closure glaucoma accompanied by high intraocular pressure. In general, reception of Nitroglycerin often must be conducted under strict medical supervision. Such instructions are given, for example, to use this drug during pregnancy and breastfeeding. Patients who receive this drug may have such side effects: reactions of the cardiovascular system – a sharp drop in blood pressure, feeling of heat, redness of the skin, increased heart rate and so on; the reactions of the digestive system – nausea, stomach pain, vomiting; reaction of the central nervous system, throbbing headaches, anxiety, disorientation; allergic rashes; impaired vision, sweating, falling body temperature, and so on. All these reactions should convince patients that Nitroglycerin should not be prescribed by themselves. This drug can be taken by a patient for extra help, in case of an acute heart attack, but long-term therapy of such conditions is prescribed by qualified professionals.
Nitroglycerin is a drug that should be in every home and travel first aid kit. Each of us should know the necessary extra dose of the drug and how to give it to the patient in case of acute attack. The thing to remember is that if you sometimes have not only pain but even discomfort in the heart area, when you breathe in, you must consult your doctor, do the necessary investigation in time to begin treatment.