The main active ingredient of Norvasc is amlodipine. Acting component of the drug belongs to a locking means that was created to block the slow calcium channels. The product provides maximum locking of the channels, thereby preventing the flow of calcium. The effect is achieved due to the binding of the active substance with dihydropyridine receptors. The result is the reduction of the amount of income of calcium into cells, which create smooth muscles of the cardiovascular system. The end result is the relaxation of the muscle tissue of the cardiovascular system.
Norvasc has antianginal, antihypertensive effect. Due to the block of slow calcium channels, it inhibits transmembrane movement of calcium ions inside cells. Its antianginal action is due to the expansion of the peripheral, coronary arteries, arterioles.
Indication for use
The drug shows the best result when it is used for the treatment of patients with stable angina, without the pain of myocardial ischemia, arterial hypertension. Norvasc gets positive feedback after the treatment of vasospastic angina, and decompensated CHF, in the latter case it is used as an adjuvant.
Method of application
The drug should be taken once per day and washed down with water.
Since the use of this drug can cause a number of side effects, the purpose of the treatment and the dosages may only be prescribed by the attending specialist. Thus, it is strictly prohibited to use Norvasc in case of the following contraindications:
- Pregnancy and lactation
- Severe hypotension
- The age of 18
- Liver failure
Side effects of Norvasc
- Depression, jaundice, amnesia, seizures
- Peripheral edema
- Frequent urination
- Pain in the abdomen
- Change of body weight
During the treatment process you need to maintain hygiene in the area of the oral cavity, and also visit a dentist.
When Norvasc was used by patients with chronic heart failure, it was noted the increase in the incidence of development of pulmonary edema.
In order to avoid the appearance of side effects and achieve maximum effectiveness of drug treatment, you must strictly adhere to the dosage and course of treatment prescribed by the attending specialist.