Drug Description

Pamelor is a tricyclic antidepressant. The main active component of this drug is Nortriptyline. It also contains such inactive components as benzoic acid, alcohol, sorbitol and cleaned water. The main action of the drug is controlling the symptoms of depression. It is known under many other names worldwide.
Pamelor is approved by Food and Drug Administration for the treatment of depression and related symptoms. Actually, the medicine can also treat nocturnal enuresis (or “bedwetting”) in kids and adults.

Essential information

In addition to its main goal (which is the treatment of depression), Pamelor fights neuropathic pain, which was confirmed by numerous clinical researches.
Moreover, this medicine can be used for the treatment of irritable bowel syndrome, panic attacks, neuralgia, chronic pain and prevention of migraine.
Even though it’s not a scientific fact, Pamelor controls the symptoms of attention deficit hyperactivity disorder in kids and teenagers. Recently, the drug became popular in the treatment of neuropathy. However, the drug can be also used for the treatment of other illnesses.


Pamelor must be taken according to the doctor’s recommendations. In some cases, the doctor can titrate the dosage to achieve maximum effect.
Patients who are going to have surgery must inform the doctor in advance, as in this case, the treatment must be stopped for a while.
To prevent the withdrawal symptoms, avoid stooping the treatment course abruptly. Reduce the dosage gradually.

Adverse effects

The wrong use of drug can cause adverse effects. The most common adverse effects are:

  • eye pain,
  • vision impairment,
  • crapms,
  • Abnormal involuntary movements of the tongue,
  • breast pain,
  • pain in the throat,
  • fever,
  • skin reddening,
  • pain during urination,
  • sickness,
  • abnormal reflexes,
  • difficulty concentrating.

The other common adverse effects are:

  • constipation,
  • chest swelling,
  • potency problems.

To reduce the severity of adverse effects, consult the doctor as soon as you note the above-mentioned adverse effects.

Drug interactions

Drug interaction can cause vertigo, thereby increasing the intensity of adverse effects. Therefore, you should avoid combining Pamelor with other drugs (especially anxiety drugs, anesthetics and antidepressants).
Patients who have used SSRI’s during the past month must avoid taking Pamelor for a maximum period after the end of the treatment course.
This antidepressant interacts with different prescription and non-prescription drugs, herbal supplements and vitamins.
Make sure you’re not allergic to any of the drug components to avoid any possible adverse effects.