Drug Description

Periactin is a drug for the treatment of allergy that belongs to the group of antihistamines. It provides the relief from allergic signs and symptoms such as sneezing, head cold, tearing, rash, itch and many other skin disorders. The drug is also known under its generic name Cyproheptadine.


This drug is also used for the treatment of different bacterial infections. Cyproheptadine 4mg is very efficient in preventing hay fever, which is one of the allergic responses. Even the patients suffering from the nightmares caused by post-traumatic stress disorder can use Periactin.
As this medicine is classified as cyproheptadine, it acts by preventing the release of histamine (a natural chemical released as a consequence of any allergic response). Moreover, it prevents another substance named serotonin.
This drug is contraindicated for children. Due to its capacity to prevent various allergic symptoms, it is classified as a broad spectrum anti-histamine medicine. Patients with diabetes, ulcer, asthma or low immunity this medication shouldn’t take this medicine. We advise you to take Periactin and start the course of treatment as soon as you note any allergic symptoms in the body.


The average dosage of the Cyproheptadine is 4mg. But the drug is also sold in the dosage of 2mg. Adult patients suffering from severe allergic response must take 4mg pill three times a day. Patients with Anorexia Nervosa must take 2mg of cyproheptadine four times a day. Your doctor can increase the dosage to 12 or even 16mg.Cyproheptadine is a very powerful antihistamine. Therefore, it must be used only in original formulation.

Skipping a dose/overdose

In case you have skipped the dosage of Periactin, take it as soon as possible. If it’s already time for the next dosage, skip the missed dose and take only the scheduled one.
Avoid taking two doses of this drug simultaneously or extra doses to compensate for the skipped dose. In case of overdose, seek immediate medical assistance.

What should you tell your doctor before beginning the treatment with Periactin?

Your doctor must prescribe the duration of treatment. It is essential to establish the due course of this drug.
You can ask your doctor about the possible adverse effects of Periactin and their severity. Inform your doctor about any medicines you’re currently taking to avoid the drug interactions.
You can also buy the generic version of this drug that costs cheaper.

Adverse Effects

If you note any allergic symptoms, such as rash, itch, shortness of breath, face swelling, you should call emergency.
Common and mild adverse effects

  • Vision impairment
  • Nausea, sleepiness and vertigo
  • Constipation and loose bowels
  • Sleeping disorders (including insomnia)
  • Perspiration
  • Frequent urination
  • Lack of appetite

Serious adverse effects

  • Cramps
  • Hallucinations
  • Increased heart rate
  • Tinnitus
  • Dark urine