Retrovir is a highly specialized antiviral drug effective against human immunodeficiency virus. The active substance – zidovudine – disrupts the construction of the viral unit, thereby suppressing the multiplication of the virus. Can be used in combination with other antiviral drugs. Over time, the human immunodeficiency virus is mutated with resistance to Retrovir. It is assigned to treat clinically significant HIV infection, as well as in HIV-infected pregnant women for more than 14 weeks of pregnancy and their children to prevent mother-to-child transmission of the pathogen. The dose, multiplicity and method of administration of the drug is determined by the doctor. It is not appointed with moderate and severe anemia, a decrease in the level of neutrophils, as well as with intolerance of the drug.
Indications for use
Combined treatment of HIV infection in children and adults together with other anti-retroviral drugs.
Retrovir is indicated for use in the case of an HIV-positive reaction in pregnant and newborns.
Method of use and dose.
Therapy by Retrovir should be started by a doctor who has experience in the treatment of HIV infection.
The nature of side effects in children and adults is similar.
Against the background of Retrovir treatment, the following side effects are observed. They can also be manifestations of the underlying disease in conjunction with other medications used to treat it. Therefore, the relationship between these effects and the use of Retrovir is difficult to assess, especially in complicated cases, characteristic of the advanced stage of HIV disease. Reduction in dose or retroviral withdrawal will be justified for the treatment of the below-mentioned side effects.
The most serious of the adverse reactions are anemia, neutropenia, leukopenia, anorexia, vomiting, abdominal pain, headaches, rash, fever, muscle pain, paresthesia, insomnia, malaise, asthenia and indigestion. They can also arise as part of the underlying disease.
- The use of Retrovir is forbidden for allergies to its components.
- The drug is contraindicated in neutropenia and hypogemoglobinaemia.
With caution, you need to use Retrovir for anemia, hepatic failure, impaired bone marrow function and in the treatment of elderly patients.