Drug Description

Serevent is a bronchodilator and is known as the brand version of Salmeterol. It is a long-acting beta2 adrenergic agonist. The inhaler has a protein binding of 96%, and its biological half-life is 5 hours. This term refers to the the time it takes for a substance to lose half of its pharmacologic, physiologic, or radiologic activity.


Serevent is used for the treatment of asthma, exercise-induced bronchospasm and chronic obstructive pulmonary disease. This drug acts by relaxing the airway muscles and facilitate breathing.

How to use this drug?

Read the instructions carefully before starting the treatment. It is inhaled orally 4 times in a day (two times in the morning and other two in the evening) or according to the doctor’s prescription. Never exhale in to the device or wash the mouth piece. Don’t use the retainer with this device. Hold the inhaler in one hand with the mouth piece facing towards you. Click once and breathe through the mouth. Hold your breath for several seconds. Take the inhaler away from the mouth and breathe out slowly. Never use it again even if you don’t feel or taste the medicine, as the repeated use may cause overdose.
If you’re using Serevent for the prevention of bronchospasm, inhale it half an hour before starting any exercise. Controller drugs are used daily and quick-relief medicines are used if the breathing gets harder. Never use it for a long time, if you suffer from thyroid diseases, cardiovascular problems, etc. If the drug isn’t useful, if you exceeded the dose or in case of aggravation of asthma, consult the doctor as soon as possible. The symptoms of overdose are: tremor, increased heart rate, insomnia, cramps, confusion, pain in the jaw or arm, mobility difficulties, upset stomach, skin rash and indigestion.
Serevent must be used only when all the other long-term drugs for the treatment of asthma prove ineffective.

Adverse Effects

The most common adverse effects are:

  • Breathing difficulty
  • Nasal congestion
  • Head pain
  • Sneezing
  • Wheezing

Less common adverse effects are:

  • Diarrhea
  • Vision impairment
  • Dryness in the mouth
  • Vertigo
  • Sleeping disorders
  • Weight loss


You can ensure the safety of this drug by avoiding drug interactions. You must stop taking certain drugs during the treatment with Nefazodone. The following medicines may cause the drug interactions with Nefazodone:

  • Antidepressants
  • Antibiotics
  • Antifungals
  • Medicines for the treatment of hepatitis C
  • Blood pressure drugs or beta blockers
  • HIV medicines, also called anti-retroviral drugs

Inform the doctor about any drugs you’re currently taking (including prescription and prescription drugs, herbal medicines and vitamins). Some drug combinations may cause negative effects. Take the drug only according to the doctor’s prescriptions to achieve maximum effect.