Loop diuretic “Torasemid” has a sufficiently high bioavailability, as well as the ability to provide a prolonged effect.
These properties lead to a number of the most favorable pharmacodynamic indicators of the drug.
In addition “Torasemid” has a marked antihypertensive effect. Also the medicine is allowed to be used for the treatment of patients with arterial hypertension as monotherapy and in combination with other antihypertensive agents.
Pharmacokinetic properties “of Torasemid” aren’t almost changed in case of such diseases as chronic hepatic or renal failure.
Side effects are quantitatively and qualitatively comparable to a number of other diuretics. All this makes the medication worthy of quite wide application in modern clinical practice.
- Edema caused by various reasons;
- Diseases of the kidneys, liver, lungs;
- Torasemid is released in the form of tablets with different dosages of active substance (5 or 10 mg). This drug is taken regular one-time during the day and you shouldn’t relate it with food. The patient can choose a convenient time and stick to it throughout the course.
- hypersensitivity to torasemid, and to any additional component of the medicament;
- hepatic coma or precoma;
- kidney failure, which is accompanied by anuria;
- violation of the process of urination that can be caused by a variety of causes;
- patients below the age of eighteen years.
During pregnancy and lactation
During pregnancy “Torasemid” can be taken only under the strict supervision of the attending physician, who should carefully weigh the potential benefit to the mother and potential risks to fetal development before prescribing this drug.
If necessary, therapy with this drug during breastfeeding period can be interrupted, after the consultation with a doctor.
The most common and well-studied side effects caused by the drug are:
- In blood plasma there is a significant increase in the number of certain liver enzymes, including glutamyl-transpeptidaza.
- The development of cardiac or cerebral ischemia, which may cause the risk of diseases such as angina, heart rhythm disturbances, and myocardial infarction. The formation of thrombosis.
- Frequent loss of consciousness.
- Lowering the amount of various blood components: red blood cells with platelets and leukocytes.
- The development of diseases of the gastrointestinal tract.
- Noticeable deterioration of appetite.
- Pain in the stomach.
- Nausea, accompanied by vomiting.
- Various manifestations of allergic reactions: severe itching, exanthema, rash and increased photosensitivity.
- It may increase creatinine and urea in the blood plasma.
- Frequent urge to urinate.
- Retention of urine, caused by expansion of the bladder.
- Cramps muscle tissue.
- Metabolic alkalosis.
- It increases the level of uric acid and glucose and various lipids in the blood plasma.
- The disturbance of the water balance.
- Electrolyte imbalance of varying severity.
- Frequent headaches.
- A large loss of fluid due to a too enhanced urination.