Drug Description

Trandane is a prescription drug that belongs to a group of nonselective beta and alpha adrenergic antagonist. It was produced by Prometheus laboratories and approved by Food and Drug Administration (1984).
The drug is administered intravenously in case of severe hypertension. Take the drug orally if you require long-term treatment. However, this drug can be taken only in small dosage.
The use of Trandane is efficient only if you follow a proper hygienic diet and maintains his weight by means of exercising.

The main function of Trandane

Trandane is mostly used for the treatment of severe hypertension, characterized by increased blood pressure with the disorders of central nervous and cardiovascular system.
The drug is also used for the treatment of post-operative and rebound hypertension (blood pressure elevation in response to stopping or reducing hypertension medications).
Particularly, Trandane can be used for the treatment of gestational hypertension accompanied by pre-eclampsia (disorder of pregnancy characterized by the high blood pressure and an increased amount of protein in the urine.).

How to use Trandane?

You can find Trandane in the following dosages: 100, 200 and 300mg. The drug can be taken irrespective of the mealtime. The initial drug dosage is 100mg, which must be taken twice a day. If you have noted no difference in 3 days, you should talk to your doctor about the increase of dosage.
In case of intravenous injection, the initial dosage is 20mg accompanied by 40 mg every ten minutes. The total daily dosage must be 300 mg a day. You should strictly follow the prescription while using Trandane. In case of overdose, seek immediate medical assistance.

Adverse effects

Common adverse effects that take place in the initial stage of treatment

  • vertigo,
  • sickness,
  • dyspepsia,
  • cold head,
  • weakness.

Other adverse effects

  • weight fluctuation,
  • pain in the chest,
  • slow heartbeat,
  • swelling of lower limbs.

If you note the aforementioned adverse effects, seek immediate medical assistance.

Drug interaction

Trandane must not be combined with antidepressants such as amitriptyline, imipramine as they can only aggravate the disease. People must not take Trandane together with the drug for the treatment of asthma.
Inform the doctor about any drug you’re taking before starting the treatment with Trandane.