The process of splitting of fats, which come with food into the body, involves the participation of a special enzyme. It depends on what proportion of fat will be absorbed and “put aside for stock”. If you block the production of enzymes, you can suspend weight gain and contribute to rapid weight loss. One of the drugs, which are based on this principle, is Xenical. It is used primarily for the treatment of obesity. Although those women who need to lose weight a little and get the perfect figure, pay attention to it.
Why Xenical is used for weight loss?
The drug is prescribed in especially severe cases. It is classified as a medicinal product, therefore independent experimentation with pills is unacceptable. But, if the doctor appoints it, you can see such advantages:
- Due to less absorption of fat, weight will quickly decrease
- Weight loss will occur without a constant feeling of hunger
- With proper administration, side effects will be minimal
In general, with the help of the drug, it is possible to eliminate factors that distract from weight loss. Regarding the last point, you must additionally be warned. Xenical is often scolded for the extensive list of its side-effects. And it is necessary to admit that it nevertheless looks rather frightening. But, if you evaluate the opinions of those who lose weight, you can still calm down. In practice, side effects do not appear so often and are not very pronounced.
Indications for use
The drug is intended for long-term use in overweight patients, in obese patients, as well as in individuals with obesity-associated risk factors.
Xenical is prescribed in combination with hypocaloric diet, patients with insulin-dependent diabetes with obesity or overweight – with a moderately limited low-calorie diet or hypoglycemic agents.
Mode of application
The drug should be taken after consulting a doctor, results of the tests, collected history. Usually, the doctor appoints 1 pill 1-3 times a day during meals or 1 hour after eating. It is not recommended to exceed the recommended dose, this can lead to side effects.
To enhance the therapeutic effect, the drug can be taken for a long time. Together with the reception of Xenical, you need to monitor your diet, go for trainings, lead an active lifestyle. The result after taking Xenical is observed in a few days, a decrease in weight sometimes reaches 6 to 15 kilograms.
Xenical should not be used in patients who have hypersensitivity reaction to any of the active or inactive ingredients of the drug. Cholecystokinin stimulates contraction of the gallbladder after its release from the mucosa of the upper part of the small intestine, which depends on the presence of free fatty acids in the lumen of the intestine. Postprandial concentration of cholecystokinin in blood plasma decreases after taking several doses of xenical in 2 of 4 studies.
Although no reduction in gallbladder contraction was noted in healthy people with normal weight during randomized, double-blind, placebo-controlled, cross-over study following a single dose of xenical, long-term effects on gallstones were not determined. Xenical is contraindicated for use in patients with cholestasis, which may be present in cases of gallbladder disease.
There were very rare cases of increased hepatic enzymes, increased alkaline phosphatase, and extremely rare cases of hepatitis. There were no causal relationship or physiological and pathological mechanisms between hepatitis and Xenical treatment.