Zocor is a hypolipidemic drug, that establishes lipid metabolism of the organism that is used to lower cholesterol. The instruction of the drug describes the features of the special treatment.
Zocor is released in the form of white tablets with a film cover, each of which can contain 40, 20 or 10 mg of active substance component of simvastatin. The auxiliary substances such drugs are: corn
starch, citric acid, magnesium stearate, lactose monohydrate and cellulose micro-crystalline.
When ingested, the active ingredient of Zocor corrects lipid metabolism, seriously reducing the content of cholesterol in blood. Moreover, the described medication improves the function of the endothelium, i.e. the inner layer of blood vessels, inhibits the growth of cells in atherosclerosis, has antioxidant activity and also helps in dissolving gall stones. Zocor has a cumulative effect, and therefore its therapeutic effect lasts 10 days, and the drug reaches its peak in the body after 5-6 weeks of treatment.
Indications for use
- hypercholesterolemia (primary, hereditary or combined dyslipidemia);
- prevention of diseases of vessels and heart (to patients with diabetes, high cholesterol and atherosclerotic disease).
The dosage of the drug
In most cases the drug Zocor is taken once in the evening. The recommended dose may vary from 5 to 80 mg depending on the disease. Most often, the initial dose is 10 mg of simvastatin, however, due to the duration of treatment, the minimum term of which is four weeks, the minimum dose can be started immediately from 30-40 mg. The maximum dose of active ingredient of the drug should not exceed 80 mg per day. The duration of treatment may only be installed by a qualified technician. Moreover, throughout the treatment the patient needs to adhere to standard hypo-cholesterol diet. Persons with inherited hypercholesterolemia should take 40 mg of Zocor in the evening or 80 mg (20 mg in the morning and afternoon, and 40 mg in the evening).
Among the unwanted conditions that may be caused by Zocor, the instruction describes: abdominal pain, constipation, diarrhea, vomiting, jaundice, headaches, disturbance of taste sensations, convulsions, dizziness, blurring of vision. In addition, Zocor can cause myodynia and some allergic reactions, for example, lupus-like syndrome, vasculitis, angioedema, urticaria, skin rash and itching. In isolated cases, this medication can cause acute renal failure or lead to reduced potency.
It is forbidden to take Zocor in the case of liver disease, lactation, during pregnancy, intolerance to simvastatin, as well as with the joint admission of Zocor and inhibitors of iso-enzyme (Ketoconazole, Itraconazole, Erythromycin, Nefazodone, Clarithromycin).
This drug is taken with caution in the case of muscular dystrophy, alcohol abuse, uncontrolled epilepsy, acute infections, surgery, hypertension, and deficiency of lactose.